Title:
ACE/ARB & CKD: Progress or Problem?
Complexity Level:
🟠

A 69-year-old woman is seen in clinic for follow-up of recently diagnosed hypertension. Her medical history is notable for stage 3 chronic kidney disease with a baseline estimated glomerular filtration rate (eGFR) of 58 mL/min/1.73 m². Urine testing demonstrates 2.6 g/day of proteinuria. She does not have diabetes mellitus.

Two weeks ago, she was started on valsartan 80 mg once daily.

At today's visit, she reports feeling well. Her blood pressure has improved from 162/82 mm Hg at the previous visit to 126/76 mm Hg. She denies dizziness, syncope, or reduced urine output.

Laboratory testing today shows:

  • Serum creatinine increased from 1.2 mg/dL to 1.5 mg/dL
  • eGFR decreased from 58 to 47 mL/min/1.73 m²
  • Serum potassium: 4.8 mmol/L

Physical examination is otherwise unchanged.

[[sd_correct]] A. Continue valsartan at the current dose and repeat renal function testing in 1–2 weeks.  [[/sd_correct]]

  [[sd_short]] [[/sd_short]]

  [[sd_long]] check video below for detailed explanation [[/sd_long]]

  [[sd_lumi]]https://app.lumi.education/api/v1/run/AkWo95/embed[[/sd_lumi]] 

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